Diprogenta: what it is, how it is used and side effects

The skin is a very important part of our body. But as with the rest of our body, it is susceptible to various injuries, illnesses and infections, and it is necessary to resort to medicine to relieve and cure the diseases that may arise.

As we know, there are many creams and drugs that are designed to treat skin problems. One of them is the diprogenta, Which we will talk about throughout this article.

    Diprogenta: what is it?

    It is called diprogenta, a strong medicine which has many effects on human skin and is used in treatment of various skin diseases. It is a substance composed mainly of betamethasone dipropionate and gentamicin sulfate, the former being a type of corticosteroid and the latter an aminoglycoside antibiotic with effect on different bacteria.

    These components therefore give diprogenta anti-inflammatory, bactericidal and vasoconstrictor effects in addition to reducing itching or itching, although its use should not exceed two weeks because prolonging excessive treatment with this substance can lead to significant side effects ( especially due to the use of corticosteroids).

    Its action is relatively fast and its effects prolonged over time, and can generally be applied once or twice a day. It’s a drug that it is marketed as a cream, The application must be made on healthy skin (never on wounds) and there is no other route of administration than the skin as this is the route by which it is best metabolized.

    Precautions should be taken to avoid ingesting it, as well as not to come into contact with the eyes. The dosage should be advised by the doctor in each case, although it is usually indicated that a thin layer of this medicine spreads.


      Diprogenta is a very useful medicine in the treatment of various skin conditions, especially those injuries and inflammations complicated by secondary infection back.

      It is commonly used in dermatoses (generic name for skin diseases), including its use in dermatitis (whether atopic, solar, seborrheic, contact, toxic or exfoliative), eczema, reactions allergic or psoriasis, reduction of inflammation and relief of itching and discomfort as well as the treatment of possible infections sensitive to the action of gentamicin.

      That yes this product it has bactericidal but not antifungal propertiesIt will therefore not be effective in diseases caused by fungi like candidiasis.

      Side effects

      As noted above, diprogenta is a strong drug, the use of which should be limited in time and applied in a very limited way, as it can lead to different side effects and even poisoning.

      Among the side effects resulting from prolonged use and in very large areas of the body, atrophy and dismemberment of the skin, dryness or maceration of the skin (weakening and softening of the skin), inflammation of the hair follicles, allergic reactions, infections, redness, acne and rashes, stretch marks, or the appearance of hair.

      Other more serious side effects would include alterations not only of the skin but of other systems and even of the development process in juveniles (which can stunt growth): this can lead to the suppression of the hypothalamic-pituitary axis. -adrenal, hyperglycemia (especially severe in diabetic patients), arterial and intracranial hypertension, worsening of glaucoma, hyperthyroidism, cholesterol, ulcer, cataracts, blurred vision, alopecia, low blood potassium or even Cushing’s syndrome. It can also cause kidney and liver damage, with prolonged use being toxic.

      Furthermore, it may also produce tolerance to gentamicinThis will facilitate subsequent infections resistant to this antibiotic.

      Contraindications and precautions

      Diprogenta is a very potent medicine which has a large number of side effects if misused, and there are a number of contraindications and precautions that should be taken into account before prescribing.

      It is contraindicated in children under the age of twelve and its use in those who have reached this age should be done with great caution. due to the possible alteration of the endocrine system and hormonal because it could have important effects on their development.

      It is also contraindicated in pregnant women (especially in the first trimester) and infants, unless the benefits outweigh the possible risks, because although in men there is insufficient data in this regard, it has been shown to generate fetuses in rats.

      Obviously, this product should not be used if you are allergic to its components. It should also not be used for fungal or viral infections., In case of tuberculosis or syphilis, inflammation of the mouth, eyes or genitals, reactions to vaccines or deep wounds.

      This product should also be avoided on large surfaces, its use in areas covered with bandages or in areas of the skin with a large number of folds, and especially its prolonged use should be avoided. Its use in psoriasis, although it may be an indication for diprogenta, should be extremely controlled and carried out under supervision. Finally, it is not recommended to mix it with substances that can interact with it.

      Bibliographical references:

      • Spanish Agency for Medicines and Health Products (2012). Flyer: information intended for the user. Diprogenta 0.5 mg / g + 1 mg / g cream. Madrid, Spain. Government of Spain; Ministry of Health, Social Services and Equality.

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